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Mounting Evidence Links GLP-1 Drugs to Serious Health Issues For years, scientific studies have showed a link between the GLP-1 drugs and increased risks of serious gallbladder-related diseases and gastrointestinal issues, including: A 2016 study of over 70,000 patients found GLP-1 drugs associated with a significantly increased risk of bile duct and gallbladder disease compared to other oral antidiabetic drugs

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A Cochrane systematic review of NAC for COPD exacerbations (39 RCTs, n=7,436) found that NAC and other mucolytics significantly reduced the frequency of acute exacerbations (OR 0.75, 95% CI 0.62-0.92) (Poole et al., Cochrane Database Syst Rev, 2019) [43]

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