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Plant-derived flavonoids are a potential source of drugs for the treatment of liver fibrosis
Funding We thank Princess Nourah Bint Abdulrahman University Researchers Supporting Project number (PNURSP2026R484), Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia
Our research has important clinical, financial, and health policy implications, as these drugs continue to be regularly discussed in the medical field and popular press." The impact of real-world data One key aspect of this research is its use of Truveta data, which draws on electronic medical records (EMRs) across 30 health systems in the U.S., including Providence
Tirzepatide is a newer weight loss and anti-obesity medication, protected by patents
[5] [2] Patients starting GLP-1 therapy should be aware of: Potential mood changes during the adjustment period, particularly if experiencing significant gastrointestinal side effects The importance of continuing existing mental health treatments unless advised otherwise by their healthcare team Realistic expectations regarding weight loss and metabolic improvements, as unrealistic goals can lead to disappointment Healthcare professionals prescribing GLP-1 agonists should: Screen for depression and anxiety at baseline and during follow-up appointments Monitor for mood changes , particularly in patients with pre-existing mental health conditions Ensure coordinated care between diabetes/obesity services and mental health teams when appropriate It is essential to recognise that GLP-1 agonists are not a substitute for evidence-based depression treatments, including psychological therapies and antidepressant medications when indicated
