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These disruptions can undermine the therapeutic benefits of dual agonism and create barriers to clinical adoption
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A separate 2024 analysis in Frontiers in Endocrinology showed that 0.5 mg weekly led to sustained weight loss and metabolic improvements over 12 months in patients with type 2 diabetes
In many of these cases, altered renal function has been reversed with supportive treatment and discontinuation of potentially causative agents
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