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Individual receptor sensitivity, baseline insulin resistance, genetic polymorphisms in GLP-1 and GIP receptors, and prior treatment duration all affect response
Sacco R, Eggenhoffner R, Giacomelli L
The internal solution for whole-cell and cell-attached recordings consisted of 126 mM K-gluconate, 10 mM NaCl, 1 mM MgCl 2 , 10 mM EGTA, 10 mM HEPES, 2 mM NaATP, and 0.1 mM Na 2 GTP, adjusted to pH 7.3 with KOH, with an osmolarity of 295300 mOsm
The study protocol received approval from the Institutional Review Board at the University of Florida, USA (Approval code: IRB201900262)
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