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10.1016/j.atherosclerosis.2010.10.023 21 KomulainenT.LodgeT.HinttalaR.BolszakM.PietilM.KoivunenP.et al (2015)

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However, be aware that the cost can be significant

Additionally, testing for biomarkers such as methylmalonic acid (MMA), may provide valuable insight and help catch B12 deficiency in the earlier stages you can also self-order an MMA lab test via Ulta Lab Tests

The evidence is unclear or shows little to no benefit from using B12 supplementation, but more research is needed in these areas