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Enzymes stay within the gastrointestinal tract and are not absorbed into the bloodstream in a way that would interfere with how the medication binds to its receptors
Consuming fewer nutrients (calories, protein, carbs, fat, and vitamins and minerals count too) for a long period of time carries the risk of certain deficiencies, adaptive thermogenesis, and the loss of valuable muscle tissue
However, the International Society of Sports Nutrition wrote that Creatine monohydrate is the most extensively studied and clinically effective form of creatine for use in nutritional supplements. Carnitine supplements can also be found in various forms, but a study published in Frontiers in Bioscience found that acetyl L-carnitine is easily absorbed and reduces inflammation, supports fat metabolism and exerts neuroprotective, neurotrophic, antidepressive and analgesic effects. The optimal dosage for creatine is three to five grams daily
