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This study clarifies a critical variable in gerotherapeutics: the route and duration of administration do not simply alter the magnitude of a drugs efficacy
CXCL1 was significantly upregulated in mice subjected to a high-fat diet (HFD) and ethanol exposure, while both CXCL1 knockout and anti-CXCL1 treatment protected these mice from neutrophil-mediated liver injury [66]
Expert Opinion on Biological Therapy, 12(1), 37-51
The available evidence is preclinical and comes from cell and animal research
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