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Lifehacks for Restless Leg or PLMD: The current research on periodic limb movement and restless leg syndrome points to a combination of increased ferroptosis in dopaminergic regions of the brain, altered or depressed circadian rhythm, elevated inflammatory cytokines, and altered dopamine/GABA levels
Additionally, he says that there aren't any existing scientific studies showing that a GLP-1 patch would work
Knowing your genetic predispositions in these peptide pathways can help guide which single agent to trial first, potentially reducing ineffective doses and supporting faster optimization
HEAR FROM A PROVIDER: DR
Some patients report temporary warmth or itching at the site
