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Analogues [edit] Several growth hormone analogues featuring amino acid substitutions, deletions, and extensions have been developed, resulting in variants with distinct pharmacokinetic and pharmacodynamic profiles

Diabetes Nutr Metab Clin Exp 1992;5(3):175-181

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Long-term safety of recombinant human growth hormone in children

The researchers found that among adults who were overweight or obese who completed the 20-week run-in period with subcutaneous semaglutide, maintaining treatment with semaglutide resulted in continued weight loss over the following 48 weeks compared to switching to placebo