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However, fluid intake targets should be individualised, particularly for people with heart failure or kidney disease who may have fluid restrictions
A recent study further identified high expression of ACSL4 is highly expressed in a UUO mouse model, and the application of an ACSL4 inhibitor demonstrated a reduction in the interstitial fibrosis response [172]
Many side effects can often be managed with proper dose escalation, hydration, nutrition counseling, and regular follow-up
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