An elevated resting heart rate can increase long-term cardiovascular risk, and regulators need robust data confirming that the metabolic benefits outweigh this potential downside
Clin Chem 41:15091517 Richie JP Jr, Skowronski L, Abraham P, Leutzinger Y (1996) Blood glutathione concentrations in a large-scale human study
By discussing the rationale behind dose conversions and the expected outcomes, healthcare providers can foster a sense of ownership and responsibility in patients, which may enhance adherence to the new regimen
Narrow Therapeutic Index Drugs: FDA Experience, Views, and Operations
Retatrutide is an investigational triple incretin receptor agonist administered as a weekly subcutaneous injection in clinical trials, with dose escalation used to improve tolerability