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Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss
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B12 is not a weight loss drug, but it can help people feel less tired, which makes it easier to be physically active and manage a healthy lifestyle
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