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Common gastrointestinal side effects including nausea, vomiting, and diarrhoea can reduce fluid intake and increase fluid losses, leading to dehydration and darker urine
Consequently, SAM/SAH is considered a useful indicator of the cellular methylation potential, and perturbation of SAM/SAH has been studied through the disruption of S -adenosylhomocysteinase activity (Liao et al., 2012)
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Appetite tends to rise when GLP-1 activity goes down
Semaglutide is not indicated for type 1 diabetes
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