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The impetus for the study occurred in the late summer of 2023 when Rizzo, a resident (study co-author Seyedeh Maryam Zekavat, MD, PhD) and other Mass Eye and Ear neuro-ophthalmologists noticed a disturbing trend three patients in their practice had been diagnosed with vision loss from this relatively uncommon optic nerve disease in just one week

[3] Specific safety considerations for concurrent use include: Cardiovascular monitoring : Regular blood pressure and heart rate checks are advisable, particularly during the first few weeks of combined use