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As with other glutathione peroxidases, GPx1 has a conserved catalytic tetrad composed of Sec or Cys, Gln, Trp, and Asn, where the Sec is surrounded by four arginines (R 57, 103, 184, 185
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Likewise, LK-935, a pyridylethanol(phenylethyl)amine derivative, binds to the heme pocket of CYP51A1, similar to azoles, and suppresses sterol synthesis in hepatoma cells [21]
Folic Acid (Vitamin B9) This vitamin is essential for red blood cell production and DNA repair and production
Heat shock proteins and neuroprotection
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