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For instance, the concomitant use of NSAIDs (non-steroidal anti-inflammatory drugs) can exacerbate kidney toxicity, which is a significant concern for those on tacrolimus therapy
In this model, Epitalon reduced the overall incidence of breast adenocarcinoma
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doi:10.1111/j.1749-6632.2010.05479.x
Interestingly, lactylation of NUSAP1 at lysine 34 prevents its protein degradation and increases its expression in PDAC cells, establishing an NUSAP1-LDHA-glycolysis-lactate loop that promotes PDAC metastasis
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