In: Kadach U, Kaufmann M, Kubli F (eds)
Comini-Frota ER, Rodrigues DH, Miranda EC et al (2012) Serum levels of brain-derived neurotrophic factor correlate with the number of T2 MRI lesions in multiple sclerosis
It is usually several of these mechanisms operating simultaneously, often amplified by stress, sleep disruption, or micronutrient insufficiencies that standard clinical follow-up doesnt capture
However, NHS access in England and Wales is more restricted under NICE Technology Appraisal 664, typically requiring referral to specialist weight management services and specific BMI/comorbidity criteria
doi: 10.1016/S0140-6736(23)02750-2 Wing RR, Phelan S