Before starting any weight loss medication, you need a proper assessment
Patients with high-risk genetic profiles receive customized dosing, slower titration, or alternative formulations to prevent anxiety before it starts
However, long-term administration of GCs at high doses is frequently associated with severe adverse effects, in particular, metabolic disorders and atrophic effects, including musculoskeletal side effects (glucocorticoid-induced osteoporosis (GIO), osteonecrosis, myopathy), disorders of carbohydrate and fat metabolism (diabetes mellitus, dyslipidemia, obesity), gastrointestinal, cardiovascular effects (Fig
We do not know whether the effects are sustained long-term
doi: 10.1007/s12011-010-8625-1 126 MatroneAFerrariFSantiniFEliseiR