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In the latter mice, the circulating IGF-I level was reduced to less than 25% of normal
GLP-1 and GIP also have extra pancreatic effects, which include a slowing of gastric emptying and central effects on the brain, leading to satiety and reduced appetite[1]
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Oxidative stress due to these free radicals containing unpaired electrons can damage cells and the DNA leading to several diseases and even cancers, dementia, Alzheimers disease, Parkinsons disease and coronary heart disease
The rate of gastric emptying during OGTT was assessed after 4 and 8 weeks of treatment (Fig
