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The FDA has stated that there is a lack of evidence to support claims of skin lightening or other benefits
404,405 In particular, reduced renal excretion leads to abnormal plasma adipokines levels including leptin and adiponectin in CKD patients
In rodents, the substance promotes the growth of new blood vessels and reduces inflammation, enhancing healing in tendons, ligaments, and muscle
Its primary research applications have focused on gut protection and musculoskeletal healing , but its mechanisms have direct relevance to eczema-damaged skin
The peptides increased skin transparency, hyaluronic acid levels, and types I and III collagen, while decreasing MMP-1/3/9, IL-1/6, and TNF-, and increasing TIMPs [35]
