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Patients who implement calorie reduction and increase their activity levels typically experience faster and more pronounced benefits than those relying on medication alone

The medication is administered as a once-weekly injection, with guidance provided on injection techniques to ensure optimal efficacy

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Embedding O 3 nanoparticles in MHPCH produced a thermoresponsive composite hydrogel (O 3 NPs@MHPCH) that lowered VEGF and inflammatory cytokines, alleviated synovitis, reduced cartilage injury, and inhibited subchondral trabecular remodeling (Wu H