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Case reports of kidney and liver toxicity have been reported when used in high doses in young men

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Notably, newborn infants are at risk of severe toxicity (as discussed in Contraindications), but in adults and older children, the small benzyl alcohol dose is very well tolerated

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In advanced AMD, choroidal neovascularisation leads to macular edema and bleeding (neovascular AMD), which can be alleviated by anti-vascular endothelial growth factor drugs [11]