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Finally, knockdown of Gln transporters (SLC38A1 and SLC1A5) or pharmacological inhibition of SLC1A5 also significantly blocked cysteine starvation-mediated ferroptosis [85, 86]

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While a similar trend was observed between tissue type, with metastatic tissue having decreased immune-cell infiltration when compared to primary tissue, immune cell type enrichment consistently differed between primary and metastatic comparisons and high and low GLP-1R comparisons, suggesting a subgroup-specific pattern of immune modulation

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