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If you were to buy into the marketing hype around GLP-1 drugs like Wegovy and Zepbound, you might believe they are a panacea for every patient who needs to lose weight, regardless of BMI
Clinical experience: Nasal glucagon (Baqsimi) is feasible for rescue indications, with bioavailability of approximately 30%40%, rapid onset suitable for hypoglycemia rescue, and needle-free administration important for caregivers treating unconscious patients ( Best fit: Very potent peptides requiring small doses, rescue medications where needle-free administration is valuable (hypoglycemia, opioid overdose), or CNS-targeted strategies where direct nose-to-brain access may offer advantages over systemic administration
Kim YC, Park JH, Prausnitz MR
And the past few quarters have been tough for the GLP market with rising price competition and supply chain issues
Timing Your Meals Around Your Semaglutide Injection Most gastroenterologists recommend eating a very light meal 1-2 hours *before* your injection, then waiting 2-3 hours after injection before eating again
