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The CDC and American Academy of Sleep Medicine recommend 7-9 hours of sleep nightly for most adults to support overall metabolic homeostasis

Beyond engaging canonical hypothalamic and hindbrain networks that control metabolic homeostasis, GLP1RAs recruit a discrete population of Glp1r -expressing neurons in the central amygdala, which selectively suppress the consumption of palatable foods by reducing dopamine release in the nucleus accumbens

they can be exacerbated by lifestyle, stress, and underlying illness

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Suppose you are over the age of 75