The question beckons what about those patients who wish to take supplemental peptides of IGF-1 etc to increase its effects
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10.3389/fmed.2022.839066 157 ZhangL.LiY.YangX.WeiJ.ZhouS.ZhaoZ.et al (2016)
A randomized controlled trial published in PMC demonstrates that older humans (71.1 years) exhibited significantly lower glutathione levels, impaired mitochondrial fatty-acid oxidation, reduced gait speed and physical function, and higher oxidative stress compared to young controls (25.5 years)