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discontinue at least 2 months before planned pregnancy [1] [3] Patients should understand that obesity is a chronic condition with biological underpinnings that persist after weight loss
Mitten, Piero Portincasa, Gyorgy Baffy eClinicalMedicine .2026
Rather than targeting obesity through a single mechanism, this 3-way agonist addresses the complex hormonal and metabolic networks that regulate body weight, treating obesity as the multifaceted metabolic disease it truly is
One practical consideration: antibiotics can worsen GI symptoms in some people, and if you are already dealing with semaglutide-related nausea or diarrhea, this overlap can be uncomfortable
Most people are surprised by how minimal the discomfort is
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