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Finding that interesting loop later led to our understanding of the sensing mechanism, Birsoy says
Low energy or brain fog
To determine which distinctive structural features can explain the relatively low GSH conjugation activity, we analyzed the 3D structure of the GSH-binding site of rTs24GST, and compared it with other GSTs of known structure, and reported K m values for GSH
The combination of reduced intake and impaired absorption creates a trajectory toward deficiency over months and years of treatment
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