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Rheumatology (Oxford), 38 , 9971002
& Liang, Y
69 Another meta-analysis of RCTs revealed that GLP-1 receptor agonist therapy lasting more than 52 weeks was linked to a significantly lower risk of fractures compared to placebo or alternative antidiabetic treatments
For researchers concerned about cardiovascular risk, practical strategies to minimize TMAO production include supporting a healthy gut microbiome through prebiotic and probiotic use, monitoring TMAO levels if testing is available, and keeping total levocarnitine exposure within studied safety ranges
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