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GLP-1RAs improve hyperglycemia by enhancing insulin secretion through increases in -cell cytoplasmic cyclic adenosine monophosphate [53], which activates protein kinase A (PKA) and, thus, increases in intracellular calcium and triggers insulin exocytosis in a glucose-dependent manner [54]
10.1046/j.1523-1755.2002.00153.x 66 KimH
Performance with such samples cannot be guaranteed, as differences in expression, sequence, tags, folding, post-translational modifications, purity, activity, or buffer composition may affect assay results
Abela, I
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