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This gradual dose escalation helps minimize gastrointestinal adverse effects
Researchers have identified dozens of contributing factors, from inherited genetic traits and disrupted hunger hormones to differences in brain signaling, metabolism, gut biology, and emotional regulation
These include nausea, gastro pain and very rarely pancreatitis
van Ruiten CC, Veltman DJ, Nieuwdorp M, IJzerman RG
However, these effects are usually manageable with the right strategies, and they typically improve significantly after the first few weeks at each new dose level
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