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The questions that Phase 3 will need to answer and that regulators will scrutinize closely include cardiovascular outcomes over extended periods, liver function changes beyond the 48-week window, potential interactions with other metabolic agents, and safety in populations not well-represented in Phase 2
(2024) 11:e01544
It is weight neutral
Factors Affecting Weight Loss Rate Several factors can influence the rate of weight loss experienced by individuals using GLP-1 medications: Dosage: Higher doses of GLP-1 medications often correlate with greater weight loss outcomes
This helps promote a calorie deficit and, therefore, weight loss
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