They have more opportunity to address psychological drivers of overeating
The article says eligibility often turns on underlying metabolic risk rather than weight alone, and names elevated fasting glucose, prediabetes, insulin resistance, elevated triglycerides and a family history of type 2 diabetes as factors that can make a lower-BMI patient a candidate
[6] Premarketing surveillance of parenteral arginine formulations identified nausea, vomiting, headache, flushing, numbness, and local venous irritation in approximately three per cent of infusions
Clinical evidence demonstrates this connection clearly
Sustained weight loss was maintained over extended treatment durations of up to 104 weeks in STEP 5 [40], while efficacy was also consistent across ethnically diverse populations, as demonstrated in STEP 6 [41] and STEP 7 [43]