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Distinct endothelial cell responses in the heart and kidney microvasculature characterize the progression of heart failure with preserved ejection fraction in the obese ZSF1 rat with cardiorenal metabolic syndrome
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Page LR, Corio RL, Crawford BE, Giansanti JS, Weathers DR
However, the sample size in that study was small, as only 16 rats (eight per group) were used in their experiment, and the study duration was short (11 days), which may have affected the statistical significance and generalizability of the results
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