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As a GLP-1 receptor agonist, Semaglutide mimics the action of the human incretin glucagon-like peptide-1 (GLP-1), thereby increasing insulin secretion and increasing blood sugar disposal and improving glycemic control
Optineurin inhibits NLRP3 inflammasome activation by enhancing mitophagy of renal tubular cells in diabetic nephropathy
Medicare currently covers GLP-1s for diabetes, sleep apnea, cardiovascular risk reduction, and MASH
These findings support the exploration of polyphenols not only in stroke prevention but also as adjuncts to enhance post-stroke recovery
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