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In the SURMOUNT-1 trial, participants without diabetes lost an average of 15-20% of their body weight over 72 weeks at the 10 mg and 15 mg doses, though results may vary in different populations
Further, to promote sustained weight management, GLP-1 RA users should be educated on healthy diets and physical activity recommendations, and support should be available to encourage long term behaviour change
Research shows that nausea affects between 15% and 50% of patients during the dose escalation phase, depending on the starting dose and how quickly the titration schedule progresses
We can compare the trials
Ozempic is not FDA-approved for weight loss, though it may be prescribed by a healthcare provider off-label to help with weight loss
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