It upregulates 1,584 genes associated with tissue repair, stem cell biology, and antioxidant defense, while downregulating 2,550 genes linked to inflammation, fibrosis, insulin resistance, and cancer metastasis
On sale
DOI: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-62025-7 Online ISBN: 978-3-030-62026-4 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)
Clinical Progress of Glutaminase Inhibitors Glutaminase inhibitors selectively target the overactive GLS in cancer cells, sparing GLS2 in normal cells: Blocking EMT (Epithelial-to-Mesenchymal Transition) : These inhibitors can help prevent EMT, which supports cancer spread
The investigators were blinded to allocation during experiments and outcome assessment