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3.3.2 Fenton reactions and the bidirectional effects of iron homeostasis imbalance Free Fe + participates in the Fenton reaction, leading to the generation of hydroxyl radicals (OH), which represents a crucial step in initiating the lipid peroxidation chain reaction (96)
As a potent tripeptide derived from the hormone alpha-melanocyte-stimulating hormone (alpha-MSH), KPV stands out for its remarkable anti-inflammatory support potential
The hydroperoxides themselves are not very reactive but are readily converted in the presence of free iron and electron donor molecules to hydroxyl and alkoxyl radicals, which indiscriminately inflict damage on biomolecules
It may activate sirtuins, a family of proteins linked to longevity and DNA repair (13)
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