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[5] Importantly, if both B12 and folate deficiencies are present, B12 should be corrected first to avoid potentially worsening neurological symptoms
Potential effects on methylation pathways and NAD+ metabolism should be considered
Despite the use of rodents and small mammals being commonplace in research, in particular for the development of novel therapeutic agents, caution still needs to be practiced when extrapolating research data to clinical applications
doi: 10.1007/s40257-014-0107-3
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