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Mice were euthanized by high-concentration isoflurane exposure or, in some cases, by overdose of ketamine/xylazine, in accordance with IACUC guidelines
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Standard oral glutathione shows only 0.7% bioavailability due to gastrointestinal degradation
doi:10.1128/msystems.00001-18 88
To become an active antioxidant again, it needs to be reduced, and it uses the energy from the NAD+ pathway to do this
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