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The dashed black curves show the responses of GSH and fractional hepatocytes to rescue by the standard dose of NAC (36 mM) given over a 1 hour time period starting at two hours after the APAP dose
This not only enhances patient compliance but also reduces the likelihood of side effects associated with more complex treatment regimens
The animals were allowed to acclimate to their new environment over the course of 5 days, followed by random assignment to an experimental treatment group
L-GSH supplementation for three months was also able to significantly decrease the levels of GSSG in PBMCs and RBCs while significantly increasing the levels of reduced form of GSH in RBCs and maintaining levels of reduced form of GSH in plasma and PBMCs
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