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This is why knowing your concentration is not optional
A balance is needed because, at high doses of 500-600 mg, caffeine can increase heart rate and shivering[9 Trusted Source 2015 - Current neuropharmacology Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug
Spermidine, in contrast, offers broader systemic benefits, particularly in terms of neuroprotection and cognitive health, while also contributing to overall longevity through its modulation of autophagy
While an attention-getting 2025 study suggested that this rebound worsened some pregnancy outcomes, the risks and benefits are still poorly understood, Dr
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