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The practical tradeoffs between the two methods come down to time, customization, and cost
FDA-approved GLP-1 peptides such as semaglutide and tirzepatide have the strongest safety data, with GoodRx confirming these prescription-only medications are safe and effective when used as directed, a status consistent with the FDA's approval of tirzepatide for chronic weight management
& Parthasarathy, S
Initial loading protocols often use daily or every-other-day dosing for the first one to two weeks, followed by weekly, then monthly maintenance
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