The solution is administered via intramuscular (IM) injection, slow intravenous (IV) injection (bolus), or IV infusion
142 Zinc deficiency (ZD) caused by knocking down ZIP10 leads to cytoplasmic p53 accumulation and nuclear translocation of AIF, ultimately triggering apoptosis
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Hussain SP, Amstad P, He P, Robles A, Lupold S, Kaneko I, Ichimiya M, Sengupta S, Mechanic L, Okamura S, Hofseth LJ, Moake M, Nagashima M, Forrester KS, Harris CC (2004) p53-Induced Up-regulation of MnSOD and GPx but not catalase increases oxidative stress and apoptosis
Moreover, use in vulnerable populations, including neonates and young children, requires careful riskbenefit evaluation to prevent GI complications and ensure safe administration (567)