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GSK3 plays a central role in DKD pathogenesis (Liang et al., 2020)
It has been investigated in experimental studies of adipose-tissue lipid metabolism, substrate oxidation, body-weight change, and beta-adrenergic-associated metabolic adaptation
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In CRC, combining 5FU with DNA-damaging agents oxaliplatin and/or irinotecan was an empirical choice rather than a rationally designed strategy, and no new combination partners have been added since the introduction of the biological EGFR and VEGF-targeting agents in the early 2000s
the GHRP-2 (Pralmorelin) is used in clinical endocrinology as a diagnostic test for pituitary GH reserve
