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A recent trial reported a significant association between elevated LPR during the first 96 h after injury and increased gray matter volume loss at 12 months after TBI (Table 1) [43]

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| Target Concentration | BAC Water to Add | Dose per 10 units on syringe | |---------------------|-----------------|------------------------------| | 8mg/ml | 3.0ml | 0.8mg | | 12mg/ml | 2.0ml | 1.2mg | | 6mg/ml | 4.0ml | 0.6mg | **Best for:** Patients on 4-8mg weekly doses (therapeutic range)