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In clinical wound-care settings, adjunct topical GHK-Cu gels were associated with larger median reductions in ulcer area and fewer recorded wound infections relative to standard care alone, particularly in larger plantar lesions that were slower to progress under routine protocols

Despite the similarly large decreases in body weight, the Sema group showed significant lean mass loss compared to the control group during the 4-week treatment period, while the Sema + -MSTN/-ActA group was not only protected against this lean mass loss, but also had a significant increase in lean mass (Fig