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Semaglutide (Ozempic, Rybelsus, Wegovy) should be discontinued in women at least 2 months before a planned pregnancy due to the long washout period for semaglutide." Additional research is underway

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Marston et al., 2019)

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The female mice (homozygous for Hba tm1(HBA)Tow and heterozygous for Hbb tm2(HBG1,HBB*)Tow and Hbb tm3(HBG1,HBB)Tow [h/h:: A / S ], sickle-cell trait mice) and male mice (homozygous for both Hba tm1(HBA)Tow and Hbb tm2(HBG1,HBB*)Tow [h/h:: S / S ], sickle SCD mice) were bred to generate SCD mice