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Its comparison with semaglutide and cardiovascular outcomes will define its benefits, potentially impacting long-term complications of type 2 diabetes

Furthermore, when apoptosis and necroptosis fail to occur, caspase-8 can be involved in the activation of caspase-1 and inflammasome to trigger pyroptosis, a strongly proinflammatory cell death modality associated with the release of IL-1 and IL-18 [145, 146]

Elevating levels of antioxidants can reduce damage due to oxidative and inflammatory stress, improving stem cell survival and efficacy

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Nomura et al., 2020)