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236 The oxidation cycle of both Prxs and GSH is directly influenced by the availability of redox cofactor NADPH, suggesting that NADPH metabolism might play a vital role in controlling redox rhythmic and transcriptional oscillations
doi: 10.1186/S12902-023-01500-5 99 LiaoMLiXZhangHZhouLShiLLiWet al
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An extension phase (NCT06780449) will assess longer-term outcomes
The peptide achieves 60% reduction in ROS levels in WI-38 cells pretreated with 10 nM-10 M GHK-Cu then exposed to 150 M hydrogen peroxide
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